Ferroptosis – and the way to inhibit it

A lot of compounds are known and available to modulate (inhibit or activate) the most prominent mode of programmed cell death – Apoptosis. In a recent post, I summarized methods to detect early Apoptosis and at the end of this post you’ll find a list of apoptosis modulators (available through tebu-bio). But there are other modes of programmed cell death, such as Autophagy (see How to manipulate and measure Autophagy), Necroptosis, and Ferroptosis.

Today I would like to focus on Ferroptosis, and invite you to take a look at the first Ferroptosis inhibitor on the market. [Read more…]