Unlimited sources of neural cells mimicking CNS disorders for in vitro bioassays

Access to neural cellular models for in vitro Neuroscience research enters into a new era.

XCell Science, experts in cellular and genome engineering, provide genetically modified cellular models differentiated from Human induced Pluripotent Stem Cell (iPSC) lines. tebu-bio bring its scientific and logistics skills to deliver in Europe these high-quality and characterized neural cell derivatives for R&D, drug discovery, toxicology and regenerative medicine approaches.

Unlimited sources of biologically relevant functional neural cells

Proprietary high-efficiency protocols allow the directed differentiation of these iPS lines into a variety of functional neural cells, such as:A large collection of neural cells (XCell Science - tebu-bio)

  • Neural Stem Cells (NSC),
  • Neurons,
  • Dopaminergic neurons,
  • Astrocytes.

Disease-specific knock-out isogenic neural cell lines

tebu-bio’s experts are pleased to introduce a collection of isogenic knock-out iPSC lines mimicking genetic defects identified in CNS disorders (Parkinson’s and Alzheimer’s diseases, Autism, Schizophrenia and Amyotrophic Lateral Sclerosis (ALS)):

  • BDNF-/-: Homozygous knockout of the BDNF gene,

    Dopa Neural Cells (XCell Science by tebu-bio)

    Expression of TH in Ready-to-use XCell DOPA cells prolonged cultured in DOPA medium.

  • APOE-/-: Homozygous knockout of the APOE gene,
  • DISC1-/-: Homozygous knockout of the DISC1 gene,
  • CNTNAP2-/-: Homozygous knockout of the CNTNAP2 gene,
  • SOD1-/-: Homozygous knockout of the SOD1 gene,
  • Park2-/-: Homozygous knockout of the Park2 gene,
  • Park7-/-: Homozygous knockout of the Park7 gene.

Want to know more about these unlimited iPSC-derived neural cellular models ?

XCell Science logo by tebu-bio

XCell Science by tebu-bio


Be among the first to receive the XCell Science launch pack by tebu-bio to optimise your in vitro CNS-specific cellular models.

Sign up now!


iPSC-derived Neural cells characterization - XCell Science by tebu-bio

iPSC-derived Neural cells characterization – XCell Science by tebu-bio

Related posts regarding CNS and Stem cell studies:



  1. […] technologies (TALEN, CRISPR) have been published (17; Xcell Science). These cellular models can mimick CNS disorders in vitro (eg. Alzheimer’s disease (AD), Parkinson’s disease (PD), Autism, Schizophrenia, and Amyotrophic […]

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