Galectin-3 (Mac-2) is a β-galactoside-binding lectin expressed in a variety of tissues and cell types (incl. activated macrophages, eosinophils, mast cells, dendritic cells, kidney cells, and sensory neurons).
Galectin-3 is a promiscuous protein modulating a diverse set of cellular functions such as cell adhesion, cell-matrix interactions, cell migration, macrophage activation, and apoptosis.
It has been described to play a role in many pathological states such as fibrosis, cardiovascular diseases and cancer.
Due to the role of galectin-3 in various pathologies, it is increasingly being investigated as a potential diagnostic marker and therapeutic target.
Being able to access well-characterized research tools enabling Galectin-3 expression studies is therefore crucial.
In this context, Cedarlane has recently released a 100% validated monoclonal antibody (clone M3/38) valid for a broad range of applications.
|Purified||Human/Mouse||Cryostat section, ELISA, FCM, IF, WB/IP||100 µg||007CL8942AP|
|Biotin||Human/Mouse||Cryostat section, ELISA, FCM, IF, WB/IP||100 µg||007CL8942B|
|FITC||Human/Mouse||FCM, IF||100 µg||007CL8942F|
|Low endotoxin||Human/Mouse||Cryostat section, ELISA, FCM, IF, WB/IP||500 µg||007CL8942LE|
Also of interest
You might also like to take a look at this range of Galectin-3 ELISA kits, available in Europe through tebu-bio.
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