The Exosome is a protein complex able to degrade the various types of RNA molecules. It can be found in eukaryotes and archaea cells.
Exosomes can be formed by all cell types and in particular lymphocytes, platelets, mast cells, dendritic cells, stem cells, astrocytes or tumor cells.
Exosomes play important roles in coagulation, waste management, and intercellular signaling. They are also used for clinical applications such as therapy, prognosis, and markers for disease. Exosomal marker antibodies detect proteins specific to the exosomes. They can help with the study of the morphology and dynamics of the exosome. A second task for this kind of antibodies is to elucidate the roles a protein may play in a number of tasks that are centered in or influenced by the exosome.
Here are 6 popular antibodies used by researchers!
This antibody specifically recognizes an epitope within the C-Terminal region of human Exosome component 9 (EXOSC9), otherwise known as PMSCL1.
This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants.
The anti-EXOSC10 is a rabbit Polyclonal antibody to exosome component 10. It is a human gene, the protein product of which is part of the exosome complex.
EXOSC3 antibody is a Rabbit Polyclonal antibody. Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex.
This antibody has been shown to work in applications such as Immunohistochemistry (fixed), Western Blot, Immunocytochemistry, Immunofluorescence.
RRP4 antibody is a Rabbit Polyclonal antibody to RRP4 (exosome component 2). Exosome component 2 is a protein which is encoded by the EXOSC2gene. EXOSC2 is a component of the human exosome. Exosome component 2 has been shown to interact with Exosome components 4 and 7.
EXOSC8 is a Rabbit Polyclonal antibody to EXOSC8 (exosome component 8).
Exosome component 8 is a human gene, the protein product of which is part of the exosome complex, and which has been shown to interact with Exosome components 5 and 6.
EXOSC10 is a Rabbit Polyclonal antibody to EXOSC10 (exosome component 10). Exosome component 10 is a human gene, the protein product of which is part of the exosome complex and is an autoantigen in patients with certain auto immune diseases.
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