Activity assays are also an area where major technological developments have been done. However, we are still missing a high-throughput approach allowing to measure the enzymatic activity of several hundred proteins at the same time. What we could call an “activity profile” of a given sample, allowing us to compare it with a control sample. In two words, Functional Proteomics.
From “Detection” Proteomics to “Functional” Proteomics
PEP for Functional Proteomics
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3. Luisa Beltran et al. J Proteomics., 2012, 77, pp. 492-503. doi: 10.1016/j.jprot.2012.09.029.